This versatile platform supports the creation of various tissue models, including tubular blood vessels, bifurcating vascular networks, renal epithelial tubules, colon tubes, and vascularized spheroids or organoids. These models can be used to study tissue barrier disruption, immune response, fibrosis and more in a highly controlled environment. With customizable designs, including three standard templates and the option for tailored configurations, AngioPlate offers unparalleled flexibility for diverse research needs. Bidirectional perfusion of tissues is achieved using the IFlowRocker, eliminating the need for pumps. For unidirectional perfusion, researchers can explore the UniPlate384 system. AngioPlate is compatible with the AngioTEER sensor, enabling realtime, continuous monitoring of tissue barrier integrity across 128 tissue units in a plate. The openwell design ensures easy access for pipetting and tissue removal for downstream analysis, while the optically clear plate bottom supports highcontent imaging using confocal microscopy and highthroughput analysis with plate readers. The 384well design also minimizes the use of cells and reagents to significantly reduce experimental costs per data point. To learn more, please visit www.organo-biotech.com/posters.  

• For non-commercial research use only.
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Product Code	A002; A002-2; A002-3
Number of Culture per Plate	128
Sterilization Method	UV sterilized
Storage Condition	Room temperature (15-25 °C)
Storage Time	3 month
Plate Format	SBS standard 384 well plate
Materials	Top plate: virgin polystyrene. Bottom plate: optical quality, low compound-absorbing plastic Internal sacrificial template: proprietary polymers
Perfusion	Gravity driven perfusion with IFlowRocker (B001)
Applications	Perfused 3D tissue and organoid culture
Readouts	Sensor (TEER with AngioTEER, B002); Imaging (phase contrast, widefield fluorescence, confocal); Plate reader (absorption, fluorescence, luminescence); Off plate (Histology, ELISA, RNA/DNA analysis, MS, biochemistry)

• 128 tissue culture units • Pump-free bidirectional perfusion • Membrane-free 3D tissue culture in hydrogel matrix • Customizable tissue architecture • Automation compatible • Low cell and media consumption